Balkanpharma Razgrad AD #Antibacterial_preparations #Preparations_for_the_treatment_of_infections #HEALTH_CARE
Product description
Tinidazole-Teva tablets are used for the indications below.
Prophylaxis
Postoperative infections caused by anaerobic bacteria, especially after surgery on the large intestine, gastrointestinal tract and after gynecological surgery.
Treatment
Eradication of Helicobacter pylori associated with duodenal ulcers - together with an antibiotic and an acid suppressant preparation.
Anaerobic infections: intraperitoneal infections (peritonitis, abscess); gynecological infections (endometritis, endomyometritis, tubo-ovarian abscess); bacterial septicemia; postoperative wound infections; infections of the skin and soft tissues; infections of the upper and lower respiratory tract (pneumonia, empyema, lung abscess). Nonspecific vaginitis. Acute ulcerative gingivitis. Urogenital trichomoniasis in men and women. Giardiasis Intestinal amebiasis. Amoebic liver damage.
Compound
The active ingredient is tinidazole (one tablet contains 500 mg of tinidazole).
Excipients: lactose monohydrate, corn starch, microcrystalline cellulose, anhydrous colloidal silicon dioxide, magnesium stearate, crospovidone; methacrylate copolymer (type A), titanium dioxide (E 171), talc, macrogol 6000, polysorbate 80.
Contraindications
Hypersensitivity to tinidazole, other derivatives of 5-nitroimidazole or any auxiliary component of the preparation.
Organic lesions of the nervous system.
Severe liver dysfunction.
Diseases of the blood, including a history (although persistent hematological disorders were not observed during clinical studies or animal studies).
First trimester of pregnancy and lactation.
Mode of application
"Tinidazol-Teva" is taken orally during or after meals with water.
The tablet should be swallowed whole. The scheme of application of the preparation "Tinidazol-Teva" depends on the indications.
Eradication of H. pylori associated with duodenal and gastric ulcers (as part of combination therapy with an antibiotic and a preparation that suppresses acid production)
Adults. The usual dose is 500 mg (one tablet) 2 times a day together with omeprazole at a dose of 20 mg 2 times a day and clarithromycin at a dose of 250 mg 2 times a day for 7 days. Clinical studies using this 7-day regimen have demonstrated a level of H. pylori eradication similar to that of omeprazole once a day.
Anaerobic infections
Adults and children over 12 years old. The initial dose is 2 g on the first day, followed by 1 g 1 time per day or 500 mg 2 times a day for 5-6 days. If it is necessary to continue therapy for more than 7 days, it is recommended to carry out a standard clinical and laboratory examination.
Children under 12 years old - do not use.
Nonspecific vaginitis
Adults. With nonspecific vaginitis, it is optimal to take 2 g once orally. For more persistent infections, 2 g can be taken for two consecutive days (total dose 4 g).
Acute ulcerative gingivitis
Adults. The recommended dose is 2 g orally as a single dose.
Urogenital trichomoniasis
If Trichomonas vaginalis infection is confirmed, simultaneous treatment of the partner is recommended.
Adults. The recommended dose is 2 g orally as a single dose.
Children over the age of 3. The recommended dose is 50-75 mg / kg body weight as a single dose. If necessary, taking the preparation can be repeated at the same dose.
Giardiasis
Adults. The recommended dose is 2 g orally as a single dose.
Children over the age of 3. The recommended dose is 50-75 mg / kg body weight as a single dose. If necessary, taking the preparation can be repeated at the same dose.
Intestinal amebiasis
Adults. The daily dose is 2 g once a day for 2-3 days.
Children over the age of 3. The daily dose is 50-60 mg / kg body weight once for 3 consecutive days.
Amoebic liver damage
Adults. The total dose varies from 4.5 to 12 g, depending on the virulence of the pathogen Entamoeba histolytica. Treatment begins with a dose of 1.5-2 g 1 time per day for three days. In the absence of the effectiveness of a three-day course of treatment, the preparation can be continued for up to 6 days.
Children aged 3 years and older: 50-60 mg / kg body weight 1 time per day for 5 consecutive days.
Prevention of postoperative infections
Adults and children over 12 years old. The dose is 2 g once orally about 12 hours before surgery.
Children under 12 years of age - not used for prophylactic purposes in children under 12 years of age.
Application features
Pregnant
There is no evidence that tinidazole is harmful during the later periods of pregnancy, but its use in the second and third trimester of pregnancy requires an assessment of the potential benefits and possible risks to the mother and fetus.
Drivers
It should be borne in mind the possibility of the appearance in rare cases of neurological symptoms such as dizziness, lack of coordination, ataxia, peripheral neuropathy or seizures, which can affect the ability to drive vehicles and work with equipment.
Overdose
Symptoms
After using a high dose of the preparation "Tinidazol-Teva", excitement, headache, tachycardia are observed. In severe cases, shock, hypotension, shortness of breath are possible.
Treatment
In case of an overdose, the stomach should be flushed and symptomatic therapy should be carried out (antihistamines, glucocorticoids), and general resuscitation measures should be taken if necessary.
There is no specific antidote. Tinidazole is easily eliminated from the body during hemodialysis.
Side effects
Reported adverse reactions, as a rule, occurred infrequently, were mild and resolved on their own.
From the gastrointestinal tract: often - nausea, vomiting, anorexia, abdominal pain, metallic taste in the mouth.
Storage conditions
Store at a temperature not exceeding 25 ° C, out of the reach of children, in a dry and dark place.
Shelf life is 3 years.
$18.89 BUY ONLINE
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