Berlin-Chemie #Pain #Headache_and_migraine #HEALTH_CARE
Indications:
MIG 400 is an anti-inflammatory and analgesic preparation (non-steroidal anti-inflammatory preparation, NSAID) that lowers fever. It is recommended for use in pain of mild and moderate intensity, e.g. dysmenorrhea, post-traumatic pain, headache, toothache, muscle pain, neuralgia and for the treatment of fever. It is intended for children over 6 years of age, adolescents and adults.
Properties:
MIG 400 is a preparation that contains ibuprofen as an active ingredient. One film-coated tablet contains 400 mg of ibuprofen. Ibuprofen is an organic chemical compound that belongs to the group of non-steroidal anti-inflammatory preparations (NSAIDs). It is a propionic acid derivative with anti-inflammatory, pain-relieving and antipyretic properties. The mechanism of its action is based on the inhibition of prostaglandin synthesis. Ibuprofen also reduces inflammation-related swelling and inhibits ADP and collagen-induced platelet aggregation. Its analgesic effect starts after approximately 30 minutes and lasts for 4 to 6 hours. It is excreted in the urine in 60-90% in the form of metabolites and does not accumulate in the body.
Composition:
The film-coated tablet contains 400 mg of ibuprofen, the tablet can be divided into two equal parts.
Use:
MIG 400 is a preparation intended for oral administration. Recommended dosage:
- Adults and adolescents over 12 years of age (≥40 kg): 200-400 mg once, daily dose 1200 mg;
- children 10-12 years (30-39 kg): 200 mg once, a daily dose of 800 mg;
- children 6-9 years (20-29 kg): 200 mg, a daily dose of 600 mg.
- The interval between doses should be at least 6 hours.
- The tablets should be swallowed whole with plenty of fluid, with or after a meal.
- Patients with a sensitive gastrointestinal tract are recommended to take the tablets with meals.
Important information:
MIG 400 is contraindicated in the case of:
- hypersensitivity to the active substance ibuprofen or any of the excipients;
- bronchospasm, asthma, rhinitis or urticaria after taking acetylsalicylic acid or other non-steroidal anti-inflammatory preparations (NSAIDs) in the history of
- nonspecific hematopoietic disorder;
- active or recurrent gastric ulcer and / or duodenal ulcer or gastrointestinal haemorrhage (two or more separate episodes of proven ulceration or bleeding);
- gastrointestinal bleeding or perforation as a consequence of a history of NSAIDs taking;
- bleeding in the brain or other active bleeding;
- severe renal or hepatic insufficiency; - severe heart failure.
It should not be used in women in the third trimester of pregnancy; in children weighing less than 20 kg (6 years), as this dose is not appropriate for this age group due to the active substance content.
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